In silico protein engineering
Master BiotechnologiesParcours Biotechnologie synthétique (BS)
Description
Objectives in terms of knowledge (course content) :
- Basics principles of molecular modelling
- Potential energy function of biological macromolecules
- Energy minimization and molecular dynamics simulations
- 3D modelling of macromolecular structures
- Role of dynamics and motion in biological function.
- Biotechnological applications of molecular modelling
Compétences visées
Objectives in terms of acquired skills :
- Students should gain enough general knowledge in modelling to understand and critically analyze a publication in the field, with relevance to biotech applications
- They’ll acquire technical knowledge in performing basic modelling task
- The goal is also to further integrate sequence-structure-function relationships of biomolecules with an understanding of bio-engineering applications