Genomics & epigenomics

  • Cours (CM) 18h
  • Cours intégrés (CI) -
  • Travaux dirigés (TD) 10h
  • Travaux pratiques (TP) -
  • Travail étudiant (TE) -

Langue de l'enseignement : Anglais

Description du contenu de l'enseignement

Objectives in terms of knowledge (course content) :
  • Genomic projects in the three domains of life and their applications
  • Sequencing and assembly of genomes
  • Genome annotation
  • Localization of genomic elements (repeats, coding and non-coding genes)
  • Number of genes, genome size and complexity, diversity of transcripts
  • Functional annotation (methods and limits)
  • Integration of omics data: from a list of genes to biological networks
  • Epigenetic regulation of eukaryotic genome expression
  • Methods to analyse epigenomes (ChIP-on-chip, ChIP-seq...)

Compétences à acquérir

Objectives in terms of acquired skills :
  • Mastery of main resources dedicated to exploration of genomes and epigenomes
  • Ability to analyse NGS data (quality control, mapping, assembly…)
  • Mastery of programs and methods commonly used in genome annotation
  • Ability to analyse and exploit a list of genes
  • Ability to use different working environments and platforms (Windows/linux, Galaxy, Ensembl, UCSC…)

Bibliographie, lectures recommandées

Bibliographie, support du cours :
  • Supports de cours en anglais et français sur la plateforme moodle de l’ENT
  • Articles de revues mis à disposition sur moodle
  • Principles of genome analysis and genomics - S.B. Primrose, R.M. Twyman. (Wiley-Blackwell)
  • Bioinformatics: sequence and genome analysis. D.W. Mount. Cold Spring Harbor Lab. Press)

Contact

Ecole Supérieure de Biotechnologie de Strasbourg

300 BOULEVARD SEBASTIEN BRANT
67412 ILLKIRCH-GRAFFENSTADEN
0368854510

Responsable

Intervenants


MASTER - Biotechnologies

Plaquette Master Biotechnologies